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albicans to invade the tissues
Care 195 , A1023 (2017)
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Obstructive lung disease (like COPD and certain neuromuscular conditions) and restrictive lung disease require different approaches
For the year ended 31 December 2025 2024 m m Profit from operations 9,997 2,736 Add: Restructuring 66 Amortisation and impairment of trademarks and similar intangibles 1,584 2,279 (Credit)/charges in respect of Romania's other taxes (15) 449 (Credit)/charges in respect of the Canada Approved Plans (708) 6,203 Impairment charges in respect of Cuba's fixed assets 74 Impairment charges relating to the Group's head office in London 75 Impairment of goodwill 277 39 Charges in connection with disposal of associate 3 6 Pension liability management (buy-out) 28 Impairment on held-for-sale assets and associated costs 235 Charges in respect of DOJ investigation and OFAC investigation 4 Credit in respect of settlement of historical litigation in relation to the Fox River (132) Loss of a distribution facility in Ukraine 39 Other adjusting items (including Engle) 66 157 Adjusted profit from operations 11,572 11,890 Impact of translational foreign exchange 364 Adjusted profit from operations, translated at 2024 exchange rates 11,936 11,890 Change in adjusted profit from operations, translated at 2024 exchange rates +0.4% Adjustments in respect of Canada1, translated at 2024 rates (308) (520) Adjusted profit from operations as adjusted for Canada, translated at 2024 exchange rates 11,628 11,370 Change in adjusted profit from operations as adjusted for Canada, translated at 2024 exchange rates +2.3% Operating Margin (Profit from operations as a % of revenue) 39.0% 10.6% Adjusted Operating Margin (Adjusted profit from operations as a % of revenue) 45.2% 46.0% Adjusted Operating Margin as adjusted for Canada (Adjusted PFO as adjusted for Canada as a % of revenue), translated at 2024 exchange rates 44.0% 44.0% 1
