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doi: 10.1016/j.jep.2024.118107 100 MouYWangJWuJHeDZhangCDuanCet al

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Concurrently, dietary intake and medication use also contribute to microbial dysbiosis

Elevated polyamine levels are necessary for neoplastic transformation and tumor progression (Casero et al., Arginine and arginine-dependent polyamine production are important not only for biomass synthesis, which supports tumor aggressiveness, but also as regulators in immunometabolism (Mondanelli et al., 2017), which represents an important target for effective cancer immunotherapy