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Amyotrophic lateral sclerosis is a non-amyloid disease in which extensive misfolding of SOD1 is unique to the familial form

The observed effects of Immunocal which have been discovered at McGill University have been evaluated by numerous independent research centers worldwide, notable in Germany, Japan, Australia, France, United States and in Nova Scotia (Canada)

One way to correct for confounding is stratification

However, theoretical concerns exist regarding interference with oxidative mechanisms intended to damage malignant cells

Without adequate collagen production and remodeling, injuries to these tissues struggle to regenerate properly, often resulting in scar tissue thats weaker and less functional than the original tissue

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