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N., Majmudar, G., et al

The very low rate constants for direct, glutathione-independent dithiol-disulfide exchange reactions between glutaredoxins and roGFP2 or other protein(S 2 )/protein(SH) 2 couples (despite favorable thermodynamics) are a prerequisite and great advantage for reliable redox measurements in vivo

(When I was on 4mg of reta, I had no appetite suppression and was actually hungrier) Hope this helps

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