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Vitamin B12 has so many functions, including the health of nerves, brain, blood and immune system, as well as the formation of DNA, B12 deficiency can impair functioning in almost any part of the body

Research documents senescence-associated gene modulation in fibroblast cultures[16]

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(CMS-4168-P)

HMGB1 can induce cytokine synthesis, stimulate chemotaxis, activate cells, and can also be an adjuvant stimulating the production of autoantibodies [251]

Clinicians frame it as supportive within a broader metabolic plan built on sleep, nutrition, recovery, and lab-guided evaluation, not as a stand-alone fat-loss shortcut