IL-1, which is secreted by macrophages and has a vital role in psoriasis immunity [22], and IL-6, which activates the JAK-STAT pathway and exhibits elevated levels in psoriasis patients lesions [23], were both significantly increased in psoriasis-induced mice
Correspondingly, ZIP13 knocking down resulted in the inhibition of human valve interstitial cells in an in vitro calcification model
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Lissoni P, Tancini G, Barni S, et al
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