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Ann Neurol 68:2836 Triantafyllou NI et al (2007) The Influence of Levodopa and the COMT Inhibitor on Serum Vitamin B12 and Folate Levels in Parkinsons Disease Patients

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Its watersoluble, 95 % purity formulation and short plasma halflife (78 minutes) allow rapid crossing of the bloodbrain barrier, where it enhances deltawave (slowwave) activity the deepest stage of restorative sleep DSIP is a nonapeptide (TrpAlaGlyGlyAspAlaSerGlyGlu) first isolated from rabbit brain and produced in the human hypothalamus

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