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IL-4 and IL-13 up-regulate CysLT2R mRNA expression more strongly in mast cells from AD patients First, we analysed the baseline CysLT2R mRNA expression in untreated mast cells from AD patients and HVs

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Disruption of the BBB has been identified as a hallmark of many neurological diseases, and therapies aimed at restoring BBB function are being developed

Interestingly, GHK alone appeared to produce a comparable stimulatory action, while copper(II) ions in isolation may indicate no such activity, suggesting the tripeptide moiety may be the primary active component, possibly reforming complexes with trace copper present in the culture medium

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