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Cells of the immune system are also highly susceptible to the cell cycle arrest and apoptotic action caused by CDT, as has been demonstrated in human T cells (Shenker et al., 1999), B cells (Sato et al., 2002), and mononuclear cells (Akifusa et al., 2001)

Using in vitro and murine tumor models, they showed that lactic acid-induced acidity enhances TGF-mediated Treg induction through a pH-dependent mechanism

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Within research settings, this peptide combination is utilized to examine interaction profiles, receptor engagement patterns, and downstream signaling responses when two distinct peptide structures are present simultaneously

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