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Although the functions of granins are still being elucidated, secretoneurin has been shown to induce mucus hypersecretion in human airway epithelial cell lines (16HBE and NCI-H292) and induce expression of muc5AC [36], suggesting a modulatory role in mucus secretion

dozens of placebo-controlled clinical trials have been carried out on pomegranate juice or pomegranate extract

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