Current Pharmaceutical Design , 16(10), 12241234
Stretched at the crest, compressed at the bottom
In one mouse study, researchers found that the peptide reduced the pain felt by the animals in their paws when placed on a mildly hot plate. The authors explained that this could be because GHK is similar in structure to cimetidine, a histamine H2 receptor antagonist sometimes given to reduce pain in certain digestive conditions.3 10 In rodents, doses as low as 0.5mg/kg were found to be effective in delivering these anti-pain effects.25 In a 70kg human, an equivalent dose would be around 5.6mg, though thats likely higher than necessary: pharmaceutical-grade GHK-Cu normally ranges from 0.5 mg to 2.5mg per injection
Want to OWN it
It's also what makes the ingredient effective at genuine remodelling rather than just adding new collagen on top of old
(PubMed) Sohal RS, Kamzalov S, Sumien N, et al