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Answer: As of April 2026, 9 mg and 12 mg weekly are the doses with confirmed Phase 3 efficacy data, both from the TRIUMPH-4 readout (26.4 percent and 28.7 percent mean weight reduction at 68 weeks, respectively)
The addition of semaglutide to this already high-risk group showed further b12 decline, but whether this represents a medication effect, dietary changes from additional appetite suppression, or natural progression of post-surgical deficiency remains unclear
Greenberg ME, Xu B, Lu B, Hempstead BL
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