Key finding: AOD 9604 reduced cartilage damage score by 67%, decreased MMP-13 activity by 58%, and preserved joint space width
In vitro laboratory use only
You can stop taking it without experiencing rebound hunger, metabolic compensation, or the rapid weight regain that characterizes some pharmacological interventions
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The BIOM file output from the DADA2 pipeline and the DECIPHER-aligned FastTree phylogenetic tree were input into QIIME (v1.9.1) and the scripts in the Supplementary Materials (QIIME Scripts compilation) were used to establish the alpha diversity metrics of Chao1 richness estimate, Simpsons evenness measure E, Shannon diversity index H, Simpsons diversity index, and Faiths phylogenetic diversity metric (whole tree) as well as the beta diversity measures of unweighted and weighted UniFrac analyses (the latter of which factors in ASV abundance 37 ) and BrayCurtis dissimilarity analysis
Be sure to document the specific abnormal findings in the medical record
