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Distinction between Acute and Chronic Effects: Relevant systematic reviews indicate that cognitive improvement is usually observed close to the time of administration in a "learning or memory retention test." This refers to the timing of the experiment, where the drug must intervene in the memory consolidation process, rather than the subjective experience that the subject can immediately feel

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J Alzheimers Dis 2019;67:469-80

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& Mavrogenis, A