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In contrast, impaired tissue glucose uptake in response to insulin (a phenomenon called insulin resistance) plays a key role in the development of type 2 diabetes (55)

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E0 cells display malignant characteristics related to drug resistance and promote tumor cell growth through interactions with fibroblasts and endothelial cells, while simultaneously suppressing immune cell infiltration ( Furthermore, EZH2, a key component of the Polycomb Repressive Complex 2 (PRC2), is closely linked to drug resistance in HGSOC

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