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An 8-week randomized double-blind clinical trial comparing GHK-Cu in nano-lipid carrier to Matrixyl 3000 showed 55.8% reduction in wrinkle volume versus control serum and 31.6% reduction versus Matrixyl 3000, with 32.8% reduction in wrinkle depth versus control

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10.1074/jbc.RA120.013478 117 NishimuraS.KiokaH.DingS.HakuiH.ShinomiyaH.TanabeK.et al (2025)

2019 Nov 22 [cited 2021 Dec 1]