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SCHEME 1 The final compounds -L-H-Glu(L-Glu-OH)OH 2 (( S , S ) 4-amino-4-carboxybutanoyl) glutamic acid) as chlorhydrate salt were obtained in 90% yield by removing N -BOC and tert butyl esters protecting groups in acidic conditions using HCl 4N aqueous solution in dioxane (Scheme 2)

N.SangeethaK.VijayalakshmiK.BarhoumA

Psychological problems may include depression, confusion, and difficulty with memory, or even dementia

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It should be noted that skilful research and processes aimed at determining the enrichment of this element in the diet will likely increase Se supplementation by people living in Egypt