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That multi-target approach is precisely what makes them interesting to researchers studying mood disorders, and it is also what makes the topic so difficult to navigate without a comprehensive guide

The selection of an animal species and model is critical in this context

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The side effects we see in clinic are generally mild: transient injection site reaction, occasional mild nausea if starting at too high a dose, infrequent headache or lightheadedness in the first week

Indeed, the link between ROS and TGF-1-induced epithelial-mesenchymal transition (EMT) has been demonstrated in endometrial cell pathology 139