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KPVs data are preclinical, concentrated in gut-inflammation models with a transporter-specific mechanism, with no confirmatory human trials

Bioactive substances in safflower flowers and their applicability in medicine and health-promoting foods

This guide gives you the grounded version

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ARA 290 at concentrations exceeding ~1 ng/mL activates the IRR, which functions as a molecular switch to provide long-lasting effects, similar to other effector molecules in the immune response

Biometals 36 (6), 11731187