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Targeting mitochondria to restore exhausted T cell antitumor function By targeting T cell mitochondria metabolism, enhancing mitochondrial biogenesis, and improving mitochondrial structure and function to restore the energy supply and function of exhausted T cells, the strategies that have been applied up to date are as follows (Table 1)
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TornatoreKMMeaneyCJAttwoodKBrazeauDAWildingGEConsiglioJDet alRace and sex associations with tacrolimus pharmacokinetics in stable kidney transplant recipients
Ann N Y Acad Sci 1019:346349 Richman PG, Meister A (1975) Regulation of gamma-glutamyl-cysteine synthetase by nonallosteric feedback inhibition by glutathione
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