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Molecular consequences of genetic variations in the glutathione peroxidase 1 selenoenzyme

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The total economic burden of cardiovascular diseases is estimated at US$177.5 billion per year (GBD 2019 Diseases and Injuries Collaborators, 2020)

Reconstituted at -80C (1 year) or 4C (short-term)

In this context, research strategies aimed at the selective inhibition of FOXO proteins including the use of peptide analogs such as FOXO4-DRI represent a promising approach for investigating the modulation of metabolic pathways, with potential relevance to diabetes-related complications