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Injections are particularly appropriate for those with: Pernicious anaemia, an autoimmune condition affecting B12 absorption Conditions affecting the stomach or small intestine, such as Crohns disease or coeliac disease Those who have had gastric surgery or bariatric procedures Strict vegans and vegetarians not meeting their B12 needs through food or oral supplements For those who can absorb B12 normally, oral supplements are generally an effective and well-evidenced alternative to injections

[DOI] [PMC free article] [PubMed] [Google Scholar] 299.A study to assess efficacy and safety of SER-287 in adults with active mild-to-moderate ulcerative colitis (ECO-RESET)

The final cell pellet was dissociated and lysed using Trizol (Invitrogen) and stored at 80 C until further use