5B), arguing that Xpd TTD/TTD is a valid fast aging model for studying the effects of FOXO4-DRI on spontaneously developed senescence in vivo
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Dehydration worsens nausea, and the vomiting and diarrhea that some researchers experience can create a dehydration cycle that amplifies symptoms
In controlled experiments, this combination of effects leads to quicker healing
Wnt/catenin is a major pathway linked to osteoblast differentiation [48,49,50,51,52] and it has been shown that in the presence of Wnt signaling, catenin accumulates in the cytoplasm and translocate to the nucleus, where it associates with Tcf/Lef transcription factors to regulate target gene expression [53,54,55,56,57,58]
