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Ehrlich solid tumor showed groups of large, round, and polygonal cells with pleomorphic shapes, hyperchromatic nuclei, binucleation, and anisocytosis

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5) have been identified: (1) ionotropic glutamate receptors, which directly gate ion channels, and (2) metabotropic glutamate receptors, which may be coupled to an ion channel or other cellular functions via an intracellular second messenger cascade

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