Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H+-ATPase (V-ATPase) with IC50 values of 4-400 nmol/mg
Adherent mammalian cells are sensitive to concentrations of 2 to 5 µg/ml
and fungus
This innovative method is not only straightforward and rapid but also requires only a small quantity of starting cultured cells or tissues
Extracted protein concentration is 1-2 mg/ml
BAFF, Soluble (human) (60-mer) (rec.) (highly active) CD40L Bafilomycin A1 (BafA1) is aBAFF is mainly produced by innate immune cells such as neutrophils, monocytes, macrophages, dendritic cells, follicular dendritic cells. T cells, activated B cells, some malignant B cells and also non lymphoid cells like astrocytes, synoviocytes and epithelial cells can also produce BAFF. BAFF binds three distinct receptors (BAFF R, TACI and BCMA) expressed predominantly on B cells, although activated T cells also express BAFF R. BAFF is a master