They are found in three isoforms and amongst them SOD1 (Cu/Zn-SOD), a predominant oxygen radical scavenger, is localized in the cytoplasm, mitochondrial intermembrane space, nucleus, and lysosomes, whereas SOD2 (Mn-SOD) and SOD3 (Cu/Zn-SOD) are localized in the mitochondrion and extracellular matrix respectively [81, 82]
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Depression Four double-blind, placebo-controlled trials have looked at the potential benefits of NAC in depression, other than BD
PM has no conflicts of interest regarding the submitted work
Chandimali N, Bak SG, Park EH, Lim H-J, Won Y-S, Kim E-K, et al
12, 2013, pp