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They are found in three isoforms and amongst them SOD1 (Cu/Zn-SOD), a predominant oxygen radical scavenger, is localized in the cytoplasm, mitochondrial intermembrane space, nucleus, and lysosomes, whereas SOD2 (Mn-SOD) and SOD3 (Cu/Zn-SOD) are localized in the mitochondrion and extracellular matrix respectively [81, 82]

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Depression Four double-blind, placebo-controlled trials have looked at the potential benefits of NAC in depression, other than BD

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PM has no conflicts of interest regarding the submitted work

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Chandimali N, Bak SG, Park EH, Lim H-J, Won Y-S, Kim E-K, et al

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12, 2013, pp

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