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Role of cytokines in intervertebral disc degeneration: pain and disc content

DAMPs released from ferroptotic cellssuch as lipid oxidation products [hydroxynonenal (4-HNE) and oxidized phospholipids (oxPLs)], HMGB1, and dsDNAactivate the TLR4-MyD88-NF-B and cGAS-STING pathways, driving the production of proinflammatory cytokines and type I interferons (Wang et al., 2019

Exacerbated mechanical hyperalgesia in rats with genetically predisposed depressive behavior: role of melatonin and NMDA receptors

AFP Politics US unveils new tariffs on 60 partners as Trump rebuilds trade agenda The United States said Thursday that it would impose new tariffs on 60 trading partners over forced labor concerns, replacing an expiring global duty rolled out by President Donald Trump earlier this year."The United States has had a forced labor import ban for nearly a century, and rigorously enforces it