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Doses used in ARA-290 human trials Study context Sarcoidosis pilot (2012) Dose & route 2 mg IV Schedule 3x/week, 4 weeks Study context Sarcoidosis SFN (2013) Dose & route Daily subQ Schedule 28 days Study context Type 2 diabetes neuropathy (2014) Dose & route 4 mg subQ Schedule Daily, 28 days Study context Phase 2b sarcoidosis (2017) Dose & route 1, 4, or 8 mg subQ Schedule Daily, 28 days Study context Diabetic macular edema (2020) Dose & route 4 mg subQ Schedule Daily, 12 weeks This is trial reporting, not a dosing recommendation

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I would have drunk urine or vomit at that moment, my mouth contorting for one more drop of life, death inching and edging its way on me, shriveling in every pore and sucking my soul out, my raspy throat stinging like bees maddened by a poker, my tongue swelling, my lungs suffocating

In sterile water, the window narrows to one to two weeks

However, this difference was not statistically significant (p=0.270)