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[20] The degree of enzyme thermolability (assessed as residual activity after heat inactivation) is much greater in 677TT individuals (1822%) compared with 677CT (56%) and 677CC (6667%)

revealed that the use of a novel REDOX selective APE1 inhibitor in vitro and in vivo could effectively reduce the progression of bladder cancer, and the combination of this inhibitor with cisplatin, a commonly used chemotherapy drug, was more effective than cisplatin alone [26]