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Pyridoxines use in pregnancy, often in combination with doxylamine, has not been associated with teratogenic effects in either the first trimester or later trimesters

Fewer Digestive Side Effects Some people experience side effects from taking oral supplements, including: Upset stomach Nausea Constipation or diarrhea Bloating These side effects are often due to the fillers and binders used in pills or the digestive stress of breaking down high concentrations of nutrients

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If caloric intake exceeds expenditure, the enhanced lipolysis may be offset by continued fat storage

Some patients report mild diarrhoea, nausea, or headache following administration, though these symptoms are usually transient