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Impaired Glutathione Recycling in Dementia As shown by Irene Martinez de Toda et al 2019 (8) data, patients with dementia have a reduction in both the enzymes (GR and GP) that recycle glutathione

Glutathione exists primarily in two interrelated forms: Reduced glutathione, or GSH: the form able to donate electrons within antioxidant and redox reactions Oxidized glutathione, or GSSG: the form produced after two glutathione molecules form a disulfide bond The body continually recycles oxidized glutathione back into reduced glutathione through enzyme systems that depend partly on cellular energy and nutrient availability

PD-1 and PD-L1 in cancer immunotherapy: clinical implications and future considerations