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It increased the relative abundance of Bacteroides while reducing Escherichia and Shigella spp., alongside upregulating occludin and downregulating claudin-2

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For non-clinical laboratory research use only not for human or animal consumption

Results Increased severity of liver injury and mortality of mice with hepsin deficiency during the early period after acetaminophen exposure To investigate the potential physiological role of endogenous hepsin in the early response to APAP-induced liver injury, we analyzed hepsin expression in wild-type mouse liver lysates following APAP treatment using western blotting (Fig