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Adding 2mL to a 5mg vial gives 2.5 mg/mL, which is easy to work with

Solutions are unstable and require refrigeration, whereas lyophilized powder (freeze-dried form) is significantly more stable

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Clock and Bmal1 encode for proteins containing bHlh-PAS domains, which form the positive arm of the feedback circuit by heterodimerizing to initiate transcription through binding to E-boxes (5-CACGTG-3) and (5-CACGTT-3) in the promoter of target genes