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doi:10.1007/s00213-019-05382-1 112 Rapado-Castro, M., Berk, M., Venugopal, K., Bush, A

The GSH redox cycle is a major source of protection against mild oxidative stress with the GPx, antioxidant enzyme that oxidizes GSH to GSSG to protect cells against the proliferation of reactive oxygen species (ROS) or reactive nitrogen species (RNS), sparing them from oxidative damage, while catalase is becoming increasingly important in protecting against severe oxidative stress [3, 6, 10]

Similarly, ER-mitochondria associations and VAPB-PTPIP51 interactions are disrupted by ALS-associated mutant FUS (Stoica et al., 2016), which results in increased production of ROS

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Anti-proliferative activity of disulfiram through regulation of the AKT-FOXO axis: A proteomic study of molecular targets

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