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Given that the IC 100 concentration of niclosamide required to completely prevent viral replication in SARS-CoV-2 infected Calu-3 lung cells as measured by Ko et al (34) as 2M, a 20uM niclosamide solution nasal spray is 10x this IC 100

Parameswaran S, Rinu PK, Kar SS, Harichandrakumar KT, James TD, Priyamvada PSP, et al

Kunsch, C

1,2 Ferroptosis exhibits unique morphological and biochemical characteristics that distinguish it from other types of cell death, 3,4 it is primarily influenced by iron homeostasis, redox balance, as well as lipid metabolism in mammalian cells

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