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Acknowledgements The authors would like to express their sincere gratitude to the Department of Applied Genetics, Karnatak University, Dharwad, for providing necessary support and resources that made this review possible
Production and purification of recombinant proteins The constructs corresponding to human FOXO4 (residues 86 206) and human p53 (residues 1 312), were purchased from Genscript in a pUC cloning vector