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SB 202190 Pack Size:10 mM * 1 mL in DMSO of which PARP-1 (and to

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Description

of which PARP-1 (and to a lesser extent PARP-2) respond to DNA-strand breaks

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SB 202190 Pack Size:10 mM * 1 mL in DMSO of which PARP-1 (and toSB 202190 is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38 and p382, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 has anti cancer activity and rescued memory deficits. SB202190 induces autophagy.

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