The process of freeze-drying (lyophilization) removes water, making them stable for shipping and storage
When your cat gets a B12 injection, it's the cyanocobalamin version
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For example, FDA labeling for cyanocobalamin injection includes contraindications (such as hypersensitivity) and important warnings (see the FDA prescribing information for cyanocobalamin injection )
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When any of those slips, the result is usually minor and short-lived, but it is worth understanding what can actually go wrong, and why we think this is a job for a clinician rather than a kitchen-table DIY