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It is proposed to work by binding GHRH receptors on pituitary somatotroph cells, prompting the pituitary to synthesize and release its own growth hormone in a pulsatile pattern, with the body's somatostatin feedback loop still intact so the effect is self-limiting rather than a constant hormone flood

Safety Profile and Important Considerations for Fat Cell Targeting Understanding how AOD-9604 targets fat cells includes recognizing safety considerations and appropriate precautions

Motus showed a high fat-to-lean loss ratio, with approximately 87% of the weight lost from fat versus lean mass in its trial population

J Clin Endocrinol Metab 2006;91:799-805

However, researchers should understand that the regulatory landscape for peptides is dynamic and evolving

A change could make things safer and secure the treatment in the long run