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This coordinated release scheme is reminiscent of neuromodulatory D-serine co-transmission at NMDA receptors, and may even suggest co-release of D-serine and polyamines from astrocytes under these conditions (with the caveat that D-serine gliotransmission is controversial) (Figure 2

While singly-housed animals may experience stress that impacts metabolism, body weight, and adiposity 65,66,67,68,69 , the singly-housed animals in this study were treated identically (to the best of the experimenters ability) to minimize and equalize stress across all animals and reduce confounding variables

So that was pretty striking

In NOD mice, SCFA supplementation further reduced islet-autoreactive T cells

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Think of it as a "repair signal" that tells your body to heal faster and better