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Free heme has also been shown to promote inflammatory gene transcription in macrophages via TLR4 and NLRP3 inflammasome signaling, which have both been implicated in worsened atherosclerosis 72,73,74,75 (Fig

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They also support liver health, which is essential for effectively metabolizing fats

This has been demonstrated in the development of several clinical candidates and approved drugs 26,27,28,29

Using a prokinetic to improve the migrating motor complex and motility through the small intestine

Supporting Cellular Homeostasis: GPx uses glutathione to detoxify peroxides, and age-related declines in this cycle mark biological aging