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doi: 10.1186/s13071-018-3164-2 162

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At 75mg daily, most protocols observe metabolic effects within 24 weeks

Acute oral toxicity assay in mice An acute oral toxicity study was performed to examine the toxicity of T1 in ICR male mice via single oral administration

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1a), and because we have previously shown 5OP regulates c-di-GMP and cellulose levels 8 , we hypothesized it is possible that the mechanism of action of 5OP is to induce l-proline starvation by competitively inhibiting l-proline binding to unknown receptors or enzymes