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Excess mitochondrial ROS production, causes cellular oxidative stress, sustains mitochondrial dysfunction and ROS production and perpetuates inflammation (Chang et al., 2021)

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Santra, M., Zhang, Z

These studies have revealed that adolescent THC exposure induces core schizophrenia-related endophenotypes resembling positive and negative symptoms, such asocial motivation deficits, affective dysregulation, cognitive and sensorimotor gating abnormalities [4, 5]