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The potential for adverse reactions is why steroids are typically reserved for very specific clinical cases or prescribed with strict medical oversight

To in response to these challenges, prodrug-based nanoparticulate drug delivery systems (PNDDS), which combines prodrug strategy and nanotechnology into a single system, resulting their many advantages, including stability for prodrug structure, the higher drug loading capacity of the system, improving the target activity and bioavailability, and reducing their untoward effects

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Lifestyle interventions to reduce chronic inflammation caused by poor diet and lack of physical activity

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