& Stocchi, V
Moderate concentrations of ROS have important signaling functions, while excessive accumulation of ROS can defeat the antioxidant system, leading to oxidative stress
While important mechanistic insights were gained to decipher the glutaredoxin-catalyzed reduction of glutathione disulfide substrates, there are still major gaps in our understanding of the enzyme mechanism regarding the reduction of non-glutathione disulfide substrates
In each heart, to every one of them, I remain a green-feathered parrot in a golden cage of memory, but when I was living each day was a smattering of eggshell fragments smeared with predators saliva
This section explains the molecular mechanism of ROS contribution to the development of disease through signaling and metabolic pathways
UPB Scientific Bulletin, Series B, Chemistry and Materials Science, 79 , 219238