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The peptide alters genes and cellular pathways related to cell growth, oxidative stress, and inflammation

Peptides with anti-inflammatory properties (BPC-157, KPV, TB-500) modulate rather than suppress inflammation, which may preserve the healing-promoting aspects of the inflammatory response while reducing its destructive elements

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To further confirm this result, we treated tendon fibroblasts with BPC 157 at different concentrations (0, 0.1, 0.25 and 0.5 g/mL) for 24 h and the expression of growth hormone receptor was found to increase in a dose-dependent manner (Figure 1A,C)

doi: 10.1200/JCO.2024.42.16_suppl.e17066 139 RodrguezHRodrguezNGallegosIArriazaCEspinoza-NavarroO