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A meta-analysis of 21 studies found that ALC improved cognitive performance in patients with mild cognitive impairment (MCI) better than placebo [22]

Relationship between sperm apoptosis signalling and oocyte penetration capacity

Alpha-lipoic acid was also less effective than pregabalin for nerve pain due to idiopathic small fiber neuropathy, chemotherapy-induced peripheral neuropathy, CharcotMarieTooth disease, post-traumatic neuropathy, and post-herpetic neuralgia (shingles)

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These results point to the need for educating family physicians and people with RA about the shift in treatment paradigms in RA, and to the need for increased rheumatologist access and manpower