Cells were cultured in Minimum Essential Medium supplemented with 10% (v/v) fetal bovine serum, 2 mmol/L l-glutamine, 1 mmol/L sodium pyruvate, 10 mmol/L HEPES, and 50 mol/L penicillin/streptomycin, and maintained at 37 C in a sterile humidified atmosphere with 5% CO 2
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Natural products in drug discovery: advances and opportunities
Kreiner D, Liu H C, Itskovitz J, et al
Tesamorelin (Egrifta, and the later reformulations Egrifta SV and Egrifta WR) is indicated to reduce excess visceral (abdominal) adipose tissue in patients with HIV-associated lipodystrophy a condition in which antiretroviral therapy and HIV itself drive an abnormal accumulation of deep abdominal fat
Clinical features include those of hyperthyroidism, as well as orbitopathy, goiter, and dermopathy/pretibial myxedema