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Further details are available on the NHANES website ( This study analyzed subsample data from twelve NHANES survey cycles conducted between 1999 and 2023 (Figure 1)

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Then, due to the proximity that macrophages and tumor cells reside in, interactions between VCAM-1 and the 4 integrins are promoted, which recruit Ezrin, a cytoplasmic adaptor protein that links the actin cytoskeleton to the cytoplasmic tail of VCAM-1, and ultimately results in tyrosine phosphorylation of Ezrin

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