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DSIP is a nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) that modulates sleep architecture by promoting stage 3/4 slow waves (delta waves) and regulating circadian rhythms

Le Semax activates the CREB (cAMP Response Element-Binding protein) signaling pathway in hippocampal neurons, leading to increased transcription of the BDNF gene

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Mol Aspects Med 30, 1328.CrossRefGoogle ScholarPubMed Bruggeman, BK, Storo, KE, Fair, HM, et al